Can Rejuran Help Acne Scars? Who Benefits and Who Needs Lasers

October 25, 2026
Can Rejuran Help Acne Scars? Who Benefits and Who Needs Lasers

Rejuran can help some acne scars, particularly shallow, soft or rolling scars and the general texture of scarred skin, but it is rarely enough on its own for deeper or more defined scars. Rejuran is a polynucleotide booster that supports skin repair and resilience. A scar-focused version exists that is designed to be injected into scar tissue. For ice pick or boxcar scars, treatments that physically remodel the skin, such as fractional lasers, subcision or chemical reconstruction techniques, usually do the heavy lifting, with Rejuran playing a supporting role.

This article explains how Rejuran works on scars, which scar types tend to respond, and why lasers and other procedures are often still needed.

Understanding Acne Scar Types

Acne scars are not all the same, and the type of scar strongly influences which treatment helps. Common categories include:

  • Rolling scars: broad, shallow depressions with sloping edges, often caused by fibrous bands pulling the skin down.
  • Boxcar scars: round or oval depressions with sharper vertical edges, which may be shallow or deep.
  • Ice pick scars: narrow, deep scars that look like small punctures.
  • Hypertrophic or keloid scars: raised scars, more common on the jaw, chest and back.
  • Post-inflammatory marks: red or brown discoloration left after acne, which is not a true textural scar.

Most people have a mixture of types, which is why combination treatment is common.

How Rejuran Works on Scarred Skin

Rejuran contains polynucleotides, purified DNA fragments derived from salmon. They are thought to:

  • Support a healthier healing environment in damaged skin.
  • Reduce low-grade inflammation.
  • Encourage collagen remodeling over time.
  • Improve overall skin thickness and resilience.

The scar-specific version is formulated to be injected directly into or under depressed scars. The idea is that the product provides a mild lifting effect and supports remodeling from within. Effects build gradually over a series of sessions.

Who Is Most Likely to Benefit

Rejuran may be a reasonable option, either alone or combined, if you:

  1. Have mostly shallow rolling scars or mild textural irregularities.
  2. Have thin or sensitive skin that recovers slowly after lasers.
  3. Want to support healing between more aggressive scar treatments.
  4. Prefer treatment with shorter visible downtime than resurfacing lasers, accepting a more modest result.
  5. Have already had laser treatment and want to refine remaining texture.

Who Usually Needs Lasers or Other Procedures

Rejuran alone is unlikely to make a major difference if you have:

  • Deep boxcar scars with sharp edges.
  • Ice pick scars, which typically need focused techniques that target each scar individually.
  • Tethered rolling scars, where fibrous bands need to be released by subcision.
  • Extensive scarring across large areas of the face.

For these cases, doctors commonly use:

  • Fractional ablative lasers such as CO2 or erbium to resurface and stimulate remodeling.
  • Fractional non-ablative lasers for gentler, gradual improvement with less downtime.
  • Subcision to release tethered scars.
  • Focal chemical techniques applied into individual narrow scars.
  • Microneedling or radiofrequency microneedling for texture and collagen stimulation.
  • Fillers or collagen stimulators to lift depressed areas in selected cases.

How Rejuran Fits into a Combined Plan

In Korea, acne scar treatment is often planned as a multi-step program. Rejuran might be used:

  • After subcision, to help support the space created under released scars.
  • Between laser sessions, to improve skin quality and resilience.
  • As a maintenance treatment once the main scar work is complete.

The exact order and timing vary by doctor and patient. Combination plans can produce better overall results than any single method, but they also require more sessions and time.

What to Expect from Treatment

The procedure

Numbing cream is usually applied. The product is injected into scarred areas using fine needles. Rejuran is known for being somewhat uncomfortable, so discuss pain control with your doctor.

Downtime

Expect small raised bumps, redness and possible bruising for one to several days. Makeup can usually be applied after a day or so, as advised.

Number of sessions

A typical course involves several sessions spaced a few weeks apart. Scar improvement is gradual and usually assessed over a few months.

Realistic results

Improvement is generally described as moderate and partial. Very few scar treatments erase scars completely; the aim is a meaningful reduction in visibility.

Safety Considerations

  • Avoid treatment during an active acne breakout in the area; controlling acne first is important.
  • Tell your doctor if you have a fish allergy.
  • Discuss any history of keloids or abnormal scarring.
  • If you take or have recently taken oral acne medications, your doctor will advise on timing for procedures.
  • Infection and persistent lumps are uncommon but possible with any injection.

Frequently asked questions

Can Rejuran replace laser for acne scars?

For mild, shallow scarring it may provide enough improvement for some people. For deeper or well-defined scars, lasers or other remodeling procedures usually provide greater change.

How soon will I see a difference?

Some people notice smoother skin after a few weeks, but scar improvement is typically judged after several sessions and a few months.

Can I do Rejuran and laser in the same trip to Korea?

Often yes, depending on the plan. Your doctor may combine them in the same session or schedule them on different days. Allow time for redness and swelling to settle before flying home.

Does Rejuran help red or brown acne marks?

Discoloration is usually better addressed with treatments for redness or pigmentation, such as vascular lasers or pigment-targeting approaches, along with sun protection.

Get a Proper Scar Assessment

The most important step in acne scar treatment is an accurate diagnosis of which scar types you have. A qualified dermatologist can examine your skin under good lighting, explain where Rejuran may help and where lasers or other procedures are needed, and build a realistic plan around your schedule.

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