Dermatology ClinicPDRN Injections in Busan, Korea What PDRN is, how it differs from PN boosters like Rejuran, and which one suits your skin
PDRN is one of the best-known ingredients in Korean skin boosters, and it is easy to confuse with PN, the ingredient in Rejuran. Both come from purified salmon DNA, but they are not the same. At JRYN Seomyeon, a doctor looks at your skin and explains which booster fits, with Rejuran Skin Booster from ₩40,000 per 1 cc on the published menu.
What are PDRN injections?
PDRN (polydeoxyribonucleotide) is a purified mix of short DNA fragments, usually taken from salmon. It was first used in medicine to support wound and tissue healing. In aesthetic dermatology it is injected in tiny amounts into the skin to help calm irritated, stressed skin and support repair, which can leave the skin more hydrated and even over a few weeks. It does not add volume and does not lift sagging.
At JRYN Seomyeon, the salmon DNA boosters listed on the clinic menu are the Rejuran range, which uses PN (polynucleotides): Rejuran Skin Booster ₩40,000 per 1 cc, Rejuran Healer ₩100,000 per 1 cc and Rejuran HB Plus ₩150,000 per 1 cc. If you are asking for a specific PDRN product, your doctor confirms whether it is available and its price at consultation.
PDRN at a glance
| What it is | Purified short DNA fragments, usually from salmon, injected into the skin |
|---|---|
| What it may help | Dull, tired or stressed skin, dryness, uneven texture, recovery after laser |
| What it does not do | Add volume, fill deep lines or lift sagging skin |
| How it is given | Many tiny injections or a fine needle device across the treated area, after numbing cream |
| Downtime | Small bumps or redness that usually settle within 1–3 days. Minor bruising is possible. |
| Sessions | Usually a short course a few weeks apart, then maintenance. Your doctor advises. |
| Related prices at JRYN | Rejuran Skin Booster ₩40,000 · Rejuran Healer ₩100,000 · HB Plus ₩150,000 (1 cc) |
| Fish allergy? | Tell your doctor before any salmon-derived booster |
PDRN vs PN: what is the difference?
Both are salmon-derived DNA fragments used to support skin repair. The size of the fragments changes how they behave in the skin.
| PDRN | PN (e.g. Rejuran) | |
|---|---|---|
| Full name | Polydeoxyribonucleotide | Polynucleotide |
| Fragment size | Shorter fragments | Longer chains |
| Texture | Thin and watery | Thicker, gel-like |
| Often chosen for | Calming stressed or irritated skin, support after laser | Thin skin, texture, elasticity and fine lines |
| Feel after treatment | Bumps settle quickly | Small bumps for 1–3 days |
| JRYN menu | Availability and price confirmed at consultation | Skin Booster ₩40,000 · Healer ₩100,000 · HB Plus ₩150,000 (1 cc) |
Product formulations differ between brands, and the research on each is still developing. Your doctor recommends a booster based on your skin, not the ingredient name. Read about salmon boosters.
A DNA booster may suit you if
- Your skin looks dull, tired or stressed
- Your skin feels dry or reacts easily
- You want to support recovery after laser treatment
- You want better skin quality rather than volume
- You are happy with gradual, natural-looking change
Your doctor may suggest another option if…
- Your main concern is volume loss or deep folds (filler or collagen stimulators may fit better)
- Your main concern is sagging (lifting may fit better)
- You have a fish allergy (tell your doctor)
- You are pregnant or breastfeeding
- You have active acne, infection or a cold sore in the area
Your booster visit at JRYN
Plan about an hour including numbing. Avoid makeup on the injected area until the next day, and skip saunas and alcohol for the rest of the day.
Skin check
In English. Your doctor looks at your skin quality, sensitivity and goals.
Choose the booster
PDRN, Rejuran (PN) or another booster, with the amount and price confirmed.
Numbing and injections
Numbing cream first, then small injections across the area.
Settle and repeat
Bumps settle in a few days. Skin quality improves over the following weeks.
Salmon DNA booster prices at JRYN
The polynucleotide boosters on JRYN’s published menu. Listed prices in Korean won.
Rejuran (PN)
| Rejuran Skin Booster | ₩40,000 | 1 cc |
|---|---|---|
| Rejuran Healer | ₩100,000 | 1 cc · 2 cc ₩180,000 |
| Rejuran HB Plus | ₩150,000 | 1 cc |
| Rejuran i (eye area) | ₩100,000 | 1 cc |
PDRN products are not listed separately on the published menu. If you want PDRN specifically, your doctor confirms availability and the price at consultation, before any treatment.
Reviewed by a JRYN doctor
Dr. Yoon Jung-wook
Managing Director, JRYN Clinic Seomyeon · Injectables and skin boosters
- Full Member, Korean Society of Aesthetic Plastic Surgery
- Full Member, Korean Society for Aesthetic Plastic Surgery & Laser Medicine
- Full Member, Korean Society of Obesity & Body Contouring
- Former Neurosurgery Resident, Dong-A University Hospital
This page is general information about PDRN Injections and does not replace an in-person consultation. Results vary between people; suitability, dose and expected results are decided by a doctor after examining you.
PDRN Injections FAQ
Still have questions? Message us on WhatsApp and we will answer in English.
What does PDRN do for the skin?
PDRN is thought to support the skin’s repair process and calm inflammation, which can make stressed, dull or dry skin look healthier over a few weeks. It is a skin quality treatment, so it will not add volume or lift sagging.
Is PDRN the same as Rejuran?
No. Both come from salmon DNA, but Rejuran uses PN (polynucleotides), which are longer chains with a thicker texture. PDRN uses shorter fragments. They overlap in what they are used for, and your doctor recommends one based on your skin.
Does JRYN offer PDRN injections?
JRYN’s published menu lists the Rejuran range of salmon DNA boosters, from ₩40,000 for 1 cc of Rejuran Skin Booster. PDRN products are not listed separately, so if you want PDRN specifically, ask on WhatsApp and your doctor will confirm availability and price.
How many PDRN sessions do I need?
Boosters like PDRN and PN usually work best as a short course a few weeks apart, followed by occasional maintenance. The number depends on your skin and goals, and your doctor gives you an estimate at consultation.
Does it hurt?
Numbing cream is applied first, so most people feel small pricks and some pressure. Areas with thin skin, such as under the eyes, can feel more sensitive.
Can PDRN be combined with laser?
Often yes. DNA boosters are commonly used alongside lasers to support skin recovery. Your doctor decides the order and timing for your skin.
Is it safe if I am allergic to fish?
Salmon-derived boosters are highly purified, but you should always tell your doctor about any fish allergy. They may suggest a different booster to be safe.
Can I have DNA boosters on a short trip?
Yes. Treatment takes about an hour including numbing, and small bumps usually settle within one to three days. Plan it early in your trip if you have photos or events.
Easy to find, easy to book.
Opening hours
| Mon · Tue · Fri | 10:30 – 20:00 |
| Wed · Thu | 10:30 – 19:00 |
| Saturday | 10:30 – 14:30 |
| Lunch (weekdays) | 13:00 – 14:30 |
| Sun & holidays | Closed |
Location
4F Samjung Tower, 672 Jungang-daero, Busanjin-gu, Busan
8 min walk from Seomyeon Station (Line 1 & 2) Exit 2, or 3 min from Seomyeon Mall Exit 16. In-building parking, first 30 minutes free.
Consult in English
Send your concern, photos and travel dates. We reply with suitable options and the price before you book.
